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PBTF Previous Year's Grant Funding

Listed below are the National and International Research Projects funded by the PBTF since 1984.

 

2006 Reseach Funded

  

  • Cornell University, Convection-enhanced delivery of recombinant immunotoxin 8H9-PE38 for the treatment of pediatric infiltrative brainstem tumors, Mark Souweidane, M.D.
  • Duke University Medical Center, Elimination of pediatric brain tumors through activation of the apoptosome, Sally Kornbluth, Ph.D.
  •  Memorial Sloan-Kettering Cancer Center, Multi-drug resistance to phenotype of the side population in medulloblastoma models, Eric Holland, M.D., Ph.D.
  •  Memorial Sloan-Kettering Cancer Center, Translation regulation by TXC2 in normal cerebellum and medulloblastoma, Anna Marie Kenney, Ph.D.
  •  Stanford University, Identification of medulloblastoma tumor stem cells using self-renewal pathways, Irving Weissman, M.D., Ph.D., and Michael Edwards, M.D.  
  • “Nicki White Memorial Grant Award” awarded in memory of Nicki White
  •  Washington University School of Medicine, Modulation of intracranial brain tumor growth and therapeutic responses by cAMP,  Joshua Rubin, M.D., Ph.D.,  

Pediatric Brain Tumor Foundation  Institute  Awards 2006

 

Pediatric Brain Tumor Foundation Institute at Duke University

Director: Darell Bigner, M.D., Ph.D.

Project 1: Establishment of Cell Lines, Xenografts and Monoclonal Antibodies, Darell Bigner, M.D., Ph.D.

Project 2: Serial Analysis of Gene Expression of Childhood Brain Tumors, Hai Yan, M.D., Ph.D.

Project 3: Altered Signal Transduction, Pathways and Small Molecule Inhibitors, Jeremy Rich, M.D.

Project 4: Gene and Radiotherapy, Michael Zalutsky, Ph.D.

Project 5: Definition of Non-AGT/DNA Mismatch Repair Deficiency Mechanisms of Resistance to Temozolomide, Henry Friedman, M.D.

Project 6: Fibro Growth Factor as a Therapy for Medulloblastoma, Rob Wechsler-Reya, Ph.D.

Project 7: Investigational New Drug and Reagent Preparation Core, Michael Granger, Ph.D.

Project 8: Tissue Bank Core, Roger McLendon, M.D.

Project 9: Pilot Project Core, Darell Bigner, M.D., Ph.D.

 

Pediatric Brian Tumor Foundation Pre- Institute Awards

 

University of San Francisco, Program on Pediatric Brain Tumor Biology and Therapeutics, Mitchel Berger, M.D., Principal Investigator.

Project 1: Central Nervous System Development and Brain Stem Glioma Tumorigenesis,

David Rowitch M.D., Ph.D., and Arturo Alverez-Buylla, Ph.D.

Project 2: Pediatric Brain Tumor Xenograft Panel, David James, Ph.D.

Project 3: MYCN and Medulloblastoma Tumorigenesis, William Weiss, M.D., Ph.D.

Project 4: Genome-based Marker and Therapy Development in Pediatric Brain Tumors,

Graeme Hodgson, Ph.D.

Project 5: Convection-enhanced and Intra-nasal Delivery of Therapeutic Agents,

Natlin Gupta, M.D., PH.D.

Project 6: Administrative and Statistical Core, Mitchel Berger, M.D.

Project 7: Tissue Bank and Neuropathology Core, Scott VandenBerg, M.D., Ph.D.

 

Childrens Hospital Los Angeles, Biology and Therapy of Pediatric Brain Tumors: Saving Lives, Saving Neurons, Robert Seeger, M.D., Principal Investigator.

Project 1: Genomics, Robert Seeger, M.D.

Project 2: Microenvironment and Angiogenesis, Anat Erdreich-Epstein, M.D., Ph.D.

Project 3: Immunotherapy, Leonid Metelitsa, MD, Ph.D.

Project 4: Experimental Therapeutics, Patrick Reynolds, M.D. Ph.D.

Project 5: Molecular Imaging, Stefan Blumi, Ph.D.

Core 1: Pathology, tissue banking and cell lines, Floyd Giles, M.D.

Core 2: Pediatric Brain Tumor Core, Anat Erdreich-Epstein, M.D., PhD.

Core 3: Imaging, Mike Rosol, Ph.D.

Core 4: Biostatistics, Richard Sposto, Ph.D.

 

Hospital for Sick Children, James Rutka, M.D., Ph.D., Principal Investigator.

Project 1: Identification of Interstitial Germline Deletions in Children with Complex Clinical Syndromes that Include Medulloblastoma, Michael Taylor, M.D., Ph.D, Eric Bouffet, M.D.

Project 2: High Resolution Genotyping of a Large Cohort of Pediatric Medulloblastomas

Michael Taylor, M.D., Stephen Scherer, Ph.D., James Rutka, M.D., Ph.D.

Project 3: Ultrahigh Resolution Genotyping of Highly Purified Medulloblastoma, Peter Dirks, M.D., Ph.D.

Project 4: Identification of Truncating Mutations in Pediatric Medulloblastoma, Peter Dirks, M.D., Ph.D., James Rutka, M.D., Ph.D., Michael Taylor, M.D., Ph.D.

 

Pediatric Brain Tumor Foundation Epedemiology Research Awards

 

Central Brian Tumor Registry of the United States - $25,000

  

2005 Research Funded

PBTF Pre-Institute Awards

  • Program on Pediatric Brain Tumor Biology and Therapeutics, Mitchel Berger, M.D., Principle Investigator
    • Project 1: Central Nervous System Development and Brain Stem Glioma Tumorigenesis, David H. Rowitch, M.D., Ph.D., and Arturo-Buvlla, Ph.D.
    • Project 2: Pediatric Brain Tumor Xenograft Panel, C. David James, Ph.D.
    • Project 3: MYCN and Medulloblastoma Tumorigenesis, William A. Weiss
    • Project 4: Genome-based Marker and Therapy Development in Pediatric Brain Tumor, J. Graeme Hodgson, Ph.D.
    • Project 5: convection-enhanced and Intra-nasal Delivery of Therapeutic Agents, Natlin Gupta, M.D., Ph.D.
    • Project 6: Administration and Statistical Core, Mitchel S. Berger, M.D.
    • Project 7: Tissue Bank and Neuropathology Core, Scott VandenBerg, M.D., Ph.D
  • Biology and Therapy of Pediatric Brain Tumors: Saving Lives, Saving Neurons: PI Robert Seeger, M.D. Children’s Hospital Los Angeles
    • Project 1: Genomics, Robert C. Seeger, M.D.
    • Project 2: Microenvironment and Angiogenesis, Anat Erdreich-Epstein
    • Project 3: Immunotherapy, Leonid Metelitsa, M.D., Ph.D,
    • Project 4: Experimental Therapeutics, Patrick Reynolds, M.D., Ph.D.
    • Project 5: Molecular Imaging, Stefan Blumi, Ph.D.
    • Core 1: Pathology tissue banking and cell lines, Floyd Giles, M.D.
    • Core 2: Pediatric Brain Tumor Core, Anat Erdreich-Epstein, M.D., Ph.D.
    • Core 3: Imaging, Mike Rosol, Ph.D.
    • Core 4: Biostatistics, Richard Sposto, Ph.D
  • Hospital for Sick Children, James Rutka, M.D., Ph.D.
    • Project 1: Identification of Interstitial Germline Deletions in Children with complex clinical Syndromes that include Medulloblastoma, Michael Taylor, M.D., Ph.D., Eric Bouffet, M.D.
    • Project 2: High Resolution Genotyping of a Large Cohort of Pediatric Medulloblastomas, Michael Taylor, M.D., Stephen Scherer, Ph.D. Jim Rutka, M.D., Ph.D.
    • Project 3: Ultrahigh Resolution Genotyping of Highly Purified Medulloblastoma, Peter Dirks, M.D., Ph.D.
    • Project 4: Identification of Truncating Mutations in Pediatric Medulloblastoma, Peter Dirks, Ph.D., Jim Rutka, M.D., Michael Taylor, M.D.
  • Pediatric Brain Tumor Foundation Institute at Duke, Director Darell Bigner, M.D., Ph.D.
    • Project One: Establishment of Cell Lines, Xenografts and Monoclonal Antibodies, P.I. - Darell D. Bigner, MD, Ph.D
    • Project Two: Serial Analysis of Gene Expression of Childhood Brain Tumors, P.I.- Hai Yan, MD, Ph.D
    • Project Three: Altered Signal Transduction Pathways and Small Molecule Inhibitors, P.I. Jeremy Rich, M.D.
    • Project Four: Gene and Radiotherapy, P.I. Michael Zalutsky, Ph.D.
    • Project five: Definition of Non-AGT/DNA Mismatch Repair Deficiency Mechanisms of Resistance of Temozolomide, - P.I. Henry Friedman, M.D.
    • Project Six: Epigenetic Regulation of Drug Resistant Genes in Medulloblastoma, P.I. – Francis Ali-Osman, D. Sc.
    • Tissue Bank Core- P.I. -Roger McLendon, M.D.
    • Investigational New Drug and Reagent Preparation- P.I. Michael Graner, Ph.D.
    • Pilot Project Core - P.I. Darell Bigner, M.D., Ph.D.

Basic Research

  • Adoptive Immunotherapy for Medulloblastoma with EFbB2-specific T Cells Stephen Gottschalk, M.D., Baylor College of Medicine
  • Identification of Genes Involved in Medulloblaastoma, Martine F. Roussel, Ph.D., St. Jude Children’s Research Hospital

Translational Research

  • Specific Antigen-Targeted Immunotherapy of medulloblastomas Darell Bigner, M.D, Ph.D., Duke University Medical Center

Epidemiological Grants

  • Central Brain Tumor Registry of the United States
  • Brain Tumor Epidemiology Consortium Meeting Scotland
  • Brain Tumor Epidemiology Consortium Meeting Chicago

Research Awards

  • Peter Steck Memorial Research Award and Lecture
  • Research Award- Hai Yan, Ph.D., Pediatric Brain Tumor Institute at Duke, Duke University Medical Center
    • Lecture- Webster Cavenee, Ludwig Institute
    • Association of Pediatric Oncology Social Workers, Education Day Award

2004 Research Funded

Basic Research

  • A Microfluidic system to Co-Localize ERK Proteins During Medulloblastoma Dispersal PI Maribel Vazquez, Sc.D. The City College of the City University of New York
  • The mechanism of ß-catenin transactivation induced by ErbB2 activation in medulloblastoma development PI Zhimin Lu,M.D., Ph.D., M.D. Anderson Cancer Center
  • Whole Genome Allele Imbalance Analysis of Pediatric glioma Using High Density SNP Array, PI Kwong-Kwok Wong, Ph.D.
  • The role of gangliosides on immunosuppression and tumourgenicity and brain tumour, Co- PI’s David Ashley MBBS, Ph.D. & Denise A. Caruso, B.S., Ph.D.

Translational Research

  • Use of a Novel SHH Pathway Inhibitor in Human Medulloblastoma Co. PI’s Tom Curran Ph.D., Richard J. Gilbertson, Ph.D.
  • Specific Antigen-Targeted Immunotherapy of medulloblastomas, Dr. Darell Bigner, M.D, Ph.D. Duke University Medical Center, Durham, North Carolina
  • Pediatric Brain Tumor Foundation Institute at Duke, Director Darell Bigner, M.D., Ph.D. 

    • Project One: Establishment of Cell Lines, Xenografts and Monoclonal Antibodies, P.I. - Darell D. Bigner, MD, Ph.D
    • Project Two: Serial Analysis of Gene Expression of Childhood Brain Tumors, P.I.- Hai Yan, MD, Ph.D
    • Project Three: Altered Signal Transduction Pathways and Small Molecule Inhibitors, P.I. Jeremy Rich, M.D.
    • Project Four: Gene and Radiotherapy, P.I. Michael Zalutsky, Ph.D.
    • Project five: Definition of Non-AGT/DNA Mismatch Repair Deficiency Mechanisms of Resistance of Temozolomide, - P.I. Henry Friedman, M.D.
    • Project Six: Epigenetic Regulation of Drug Resistant Genes in Medulloblastoma, P.I. – Francis Ali-Osman, D. Sc.
    • Tissue Bank Core- P.I. -Roger McLendon, M.D.
    • Investigational New Drug and Reagent Preparation- P.I. Michael Graner, Ph.D.
    • Pilot Project Core - P.I. Darell Bigner, M.D., Ph.D.

Epidemiology Grants

  • Central Brain Tumor Registry of the United States
  • Brain Tumor Epidemiology Consortium Meeting

Research Awards

  • Peter Steck Memorial Research Award & Lecture, M.D. Anderson Cancer Center
  • Young Investigator Award, Michael D. Taylor, M.D., Ph.D. St. Jude Children’s Research Hospital
  • Lecture Award, Tak W. Mak, Ph.D. Professor of Medical Biophysics, University of Toronto
  • Society of Neuro Oncology Pediatric Brain Tumor

Basic Research

  • Award of Excellence, Michael Taylor, M.D., Fellowship - St. Jude Children's Research Hospital
  • Society of Neuro Oncology Foundation Sustaining Partners Award
  • American Association of Neuro-Surgeons/CNS Bi-annual Meeting
  • Best Resident Abstract Award – Avinash L. Mohan, M.D.
  • Association of Pediatric Oncology Social Workers, Education Day Award

Research Meeting Sponsor

  • Society of Neuro-Oncology

2003 Research Funded

  • Pediatric Brain Tumor Foundation Institute at Duke - Dr. Darell Bigner, M.D., Ph.D. - Director

    • Project One: Establishment of Cell Lines, Xenografts and Monoclonal Antibodies, P.I. - Darell D. Bigner, MD, Ph.D
    • Project Two: Serial Analysis of Gene Expression of Childhood Brain Tumors, P.I.- Hai Yan, MD, Ph.D
    • Project Three: Altered Signal Transduction Pathways and Small Molecule Inhibitors, P.I. Jeremy Rich, M.D.
    • Project Four: Gene and Radiotherapy, P.I. Michael Zalutsky, Ph.D.
    • Project five: Definition of Non-AGT/DNA Mismatch Repair Deficiency Mechanisms of Resistance of Temozolomide, - P.I. Henry Friedman, M.D.
    • Tissue Bank Core- P.I. -Roger McLendon, M.D.
    • Investigational New Drug and Reagent Preparation- P.I. Carol Wickstrand, Ph.D.
    • Pilot Project Core - P.I. Darell Bigner, M.D., Ph.D.

Basic Research

  • Anti-tumor effects of ARF Tumor Suppressor Gene on Human glioblastoma Formation, P.I. -Erwin Van Meir, Ph.D., Emory University
  • Genetic Susceptibility in Pediatric Brain Cancer, P.I. - Jan M. Van Tornout, MD, MS – Children’s Hospital Los Angeles
  • The role of Hormones in Regulating medulloblastoma Cell Growth, P.I. - Scott M. Belcher, Ph.D. - University of Cincinnati College of Medicine

Translational Research

  • Specific Antigen-Targeted Immunotherapy of medulloblastomas
    Dr. Darell Bigner, M.D, Ph.D. Duke University Medical Center
    Durham, North Carolina

Epidemiology Research

  • Central Brain Tumor Registry of the United States, Sustaining Grant

Research Awards

  • Peter Steck Memorial Research Award and Lecture

    • Juan Fueyo, M.D. - MD Anderson Cancer Center - Research Award
    • Ron DePhino, MD, Harvard Medical School - Lecture
  • Society of Neuro Oncology Pediatric Brain Tumor

Basic Research

Awards of Excellence

    • Erik J. Uhlmann, MD, Washington University School of Medicine
    • Association of Pediatric Oncology Social Workers, Education Day Award

Research Meetings

  • International Symposium on Pediatric Neuro Oncology
  • 16th International Meeting on Brain Tumor Research and Therapy

2002 Research Funding

Basic Research

  • Anti-angiogenic Immunotherapy of Malignant Brain Tumor
    John Sampson, M.D., Ph. D. Duke University Medical Center
    Durham, North Carolina
  • Modulation of the Shh/Ptc/Gli1 Signaling Pathway during Normal and Neoplastic Proliferation in the Nervous System Cynthia Wetmore, M.D., Ph.D., Mayo Clinic Rochester, New York
  • The Role of Glia in Medulloblastoma J.T. Rutka, M.D., Ph.D., FRCSC,FACS, FAAP Hospital for Sick Children Research Institute
    Toronto, Ontario, Canada
  • Molecular and In Vivo Analyses of Glioma Apoptotic Pathways
    David Ashley, MBBS, Ph.D., FRACP, Royal Children's Hospital
    Victoria, Australia

Clinical Research

  • Loss of Coordinate Regulation of Migration and Proliferation in Medulloblastoma, PI Rosalind A. Segal, M.D., Ph.D., Dana Farber Cancer Institute Boston, Massachusetts
  • A genetically Engineered HS-1Vector, G207, for the Treatment of Malignant Pediatric Brain Tumors PI Alyssa T. Reddy, M.D., University of Alabama Birmingham

Translational Research

  • Specific Antigen-Targeted Immunotherapy of medulloblastomas
    Dr. Darell Bigner, M.D, Ph.D. Duke University Medical Center, Durham, North Carolina

Epidemiology Research

  • Central Brain Tumor Registry of the United States – Sustaining Grant

Research Awards

  • Association of Pediatric Oncology Social Workers, Education Day Award
  • Society of Neuro-Oncology Pediatric Brain Tumor Research Awards of Excellence
  • Peter Steck Memorial Research Award and Lecture

    • Research Award – Roger Abounader, Ph.D.,
    • Research Lecture – Tom Curran, Ph.D., St. Jude Children’s Hospital

Research Meetings

  • International Symposium on Pediatric Neuro-Oncology
  • International Meeting on Brain Tumor Research and Therapy

2001 Research Funding

Basic Research

  • Analysis of Notch Pathway Quantitative Trait Loci in D. Melanogaster PI Hugo Bellen, DVM, Ph.D., Baylor College of Medicine
    Houston, Texas
  • Replicating Adenoviruses for Glioma Treatment
    Juan Fueyo, M.D. MD Anderson Cancer Center Houston, Texas
  • Molecular Effects of Radiation on Young Brain
    Glenn T. Gobbel, D.V.M., Ph.D., University of Pittsburgh
    Pittsburgh, Pennsylvania

Translational Research

  • Specific Antigen-Targeted Immunotherapy of medulloblastomasDr. Darell Bigner, M.D, Ph.D. Duke University Medical Center Durham, North Carolina

Clinical Research

  • Neural Sequelae of Pediatric Brain Tumor: an fMRI Study Robert Ogg, Ph.D.,St Jude Children Hospital, Memphis, Tennessee

Clinical Fellowship

  • Molecular Pathogenesis of Medulloblastoma, Jack M. Su, M.D. Baylor College of Medicine, 100,000

Epidemiological Research

  • Central Brain Tumor Registry of the United States, Sustaining Grant

Research Awards

  • Society of Neuro-Oncology Pediatric Brain Tumor Research Awards of Excellence
  • Peter Steck Memorial Research Award and Lecture

Research Meetings

  • 15th International Meeting on Brain Tumor Research and Therapy
  • International Meeting on Pediatric Neuro-Oncology

2000 Research Funded

Basic Research

  • Cytosine Deaminase-Secreting Adenovirus for Brain Tumor Therapy, Yancey Gillespie, M.D., Ph.D., University of Alabama Birmingham, $70,000
  • A Conditional Mouse Model for Medulloblastoma, Mario R. Capecchi, Ph.D., University of Utah School of Medicine
  • Development of a Model of Human Fetal Astrocyte Transformation, Jeremy N. Rich, M.D., Duke University Medical Center
  • Genetic analysis of INI1 in central nervous system rhabdoid tumors, Jaclyn A. Biegel, Ph.D., Children’s Hospital of Philadelphia
  • Somatic Cell Gene Transfer to model Medulloblastoma in Mice, Daniel W. Fults, M.D., University of Utah School of Medicine

Clinical Research

  • Amifostine: Potential cytoprotectant Against Cisplatin-Induced Ototoxicity in Children with Medulloblastoma/PNET, Maryam Fouladi, M.D., St. Jude Children’s Research Hospital

Translational Research

  • Specific Antigen-Targeted Immunotherapy of medulloblastomas Dr. Darell Bigner, M.D, Ph.D. Duke University Medical Center

Epidemiology

  • Central Brain Tumor Registry of the United States – Sustaining Grant

Awards

  • Society of Neuro-Oncology Pediatric Brain Tumor Research Awards of Excellence
  • Peter Steck Research Award and Lecture
  • Peter Steck Memorial Research Award– Eric Holland, M.D, Ph.D., MD Anderson Cancer Center
  • Peter Steck Memorial Lecture – Goeffrey Wahl, Ph.D., Salk Institute

1999 Research Funded

Basic Research

  • Vaccine approaches to Glioma Therapy Directed to EGFRvlll, PI Carol Wickstrand, Duke University Medical Center
  • Comparative analysis of Medulloblastoma in Humans and ptc +/-, PI Cynthia Wetmore, St. Jude Research Hospital
  • MAP-Kinase Dependent Triggering of Senescence in Pediatric and Adult Low Grade Glioma, PI Russell Pieper, University of California San Francisco
  • Evaluate the Regulation and Therapeutic Potential of Microsomal Epoxide Hydrolase in Human Brain Tumors, PI Erwin Van Meir, Emory University
  • Genetics of glioma Cell Invasion PI Michael E. Berens, Barrow Neurological

Clinical Research

  • DNA Repair Deficiency Induced by p53 and its Rational Exploitation for Improved Therapy of Pediatric Gliomas, Kalkunte S. Sirvenugopal, Ph.D., MD Anderson Cancer Center
  • Improvement in quality of life using a problem-solving intervention for parents of pediatric brain tumor patients: Relationship with neurocognitive deficits, Elana Farace, Ph.D., University of Virginia

Epidemiology

  • Central Brain Tumor Registry of the United States – Sustaining Grant

Awards

  • Society of Neuro-Oncology Pediatric Brain Tumor Research Awards of Excellence

Research Meetings

  • 14th International Conference on Brain Tumor Research and Therapy

1998 Research Funded

Basic Research

  • Analysis of the Sonic Hedgehog Pathway and its Downstream Targets, Duke University medical Center, PI Gregory J. Riggins, M.D., PH.D.
  • The Characterization of SPARC and Vitronectin in Astrocytic Tumor Cell Migration: PI Henry Ford Health System, Sandra A. Remple, Ph.D.
  • Cytokine-Enhanced Local Immuno/Chemotherapy of Malignant Brain Tumors PI Johns Hopkins University, Alessandro Olivi, M.D.
  • Mutagen Sensitivity as a Prognostic Marker in Pediatric Tumor Patients: Pi M.D. Anderson Cancer Center, Qingyi Wei
  • Evaluation of Genetic Markers for the Diagnosis and Prognosis of Pediatric Malignant Astrocytomas, PI Mayo Clinic and Foundation, David James, Ph.D.

Clinical Research Grants

  • Pediatric Brain Tumor Consortium, Grant for start of PBTC Neuro Imaging Center

Epidemiology

  • Conversion of CBTRUS Rates to the Year 2000 Standard: PI, Faith Davis, Ph.D., Central Brain Tumor Registry of the United States
  • Medical Research Journal "Neuro-Oncology Journal founding Grant, Society of Neuro-Oncology
  • Publication Grant – Proceeding of the International Conference on Glutathione and glutathione-Linked Enzymes in Human Cancer and Other Diseases" Francis Oli- Osman, D.Sc. M.D. Anderson Cancer Center

1997 Research Funded

Basic Research

  • Apoptosis in Medulloblastoma: Regulation by Id Genes and clinical Significance PI Mark A. Israel, M.D., University of California San Francisco,
  • Cytokine Expressing Recombinant Herpes Simples PI, Yancey Gillespie, PH.D. University of Alabama at Birmingham
  • Two–Dimensional Genome Scanning of Pilocytic Astrocytomas, PI, H.-J. Su Huang, Ludwig Institute Cancer Center
  • Role of the Transcriptional repressor REST/NRSF in Blocking Differentiation of Medulloblastoma, PI Sadhan Majumder, Ph.D, M.D. Anderson Cancer Center, Majumder
  • PTCH/Sonic Hedgehog and Beta-catenin Pathway Alternations in PNET PI, Corey Raffel, M.D., Ph.D. Mayo Clinic and Foundation

Epidemiology

  • Central Brain Tumor Registry of the United States, Sustaining Grant.
  • After completion of Therapy Clinic for Childhood Cancer Survivors–PI Orren Beaty, III, D.O., Ph.D., Ruth and Bill Graham Children’s Hospital

Research Meetings

  • 13th International Meeting on Research and Therapy
  • International Symposium on Pediatric Oncology Research

1996 Research Funded

Basic Research

  • PAX Genes in Pediatric Brain Tumors, PI, Peter A. Steck, PH.D., MD Anderson Cancer Center
  • Pediatric Brain Tumors: Classification and treatment, PI, M. Sue O’Dorisio, M.D, Ph.D.
  • Evaluation of the Efficacy and Toxicity of Irradiated, Cytokine-Producing Tumor Cells As Vaccines Against Intracerebral Gliomas, PI Darell D. Bigner, M.D., Ph.D.Medulloblastoma Growth Regulation by neurotrophin Receptor Activation PI, Scott Pomeroy, Children’s Hospital Harvard Medical School
  • Allelic Loss as a Predictor of Outcome in Archival Pediatric Brain Tumor Specimens, PI Philip H. Cogen, M.D., Ph.D.
  • Convection- Enhanced Delivery of Antisense Oligonucleotides for Suppression of Angiogenesis in Experimental Brain Tumors PI Dennis Groothuis, M.D., Evanston Hospital

1995 Research Funded

Basic Research

  • Tumor Vaccination with Mutant Epidermal Growth Factor Receptor, PI Glenn Dranoff, M.D., Dana Farber Cancer Center
  • Cyclophosphamide Resistance in Childhood Medulloblastoma PI, Henry Friedman, M.D., Ph.D. Duke University
  • HLH Genes in the Pathogenesis of Childhood CNS Tumors, PI, Mark A. Israel, M.D., University of California San Francisco
  • Research Fellowship, PI Anthony Montgomery, PH.D., Scripps Research Institute
  • Society of Neuro-Oncology

1994 Research Funded

Basic Research

  • Basic Brain Tumor Research, PI Victor Levin, MD Anderson Cancer Center,
  • The Cellular Response to DNA Damage: A role for p53-independent apoptosis and p53-dependent G1-arrest in radiosensitivity, PI Hass-Kogan, D.A., Mark Israel, M.D., University of California San Francisco
  • Neuropeptide and Neuropeptide receptor Gene Expression in Pediatric Brain Tumors, PI Dr. Sue O’Dorisio, M.D., PH.D., Children Hospital Columbus Ohio
  • Genetic Bases of Growth Regulatory Genes in Gliomas, PI Long-Sheng Chang, Ph.D., Herbert B. Newton, M.D., Ohio State Brain Tumor Research Program
  • Duke University Medical Center, PI Henry Friedman, M.D, Ph.D.
  • American Brain Tumor Foundation, Research Fellowships
    • Robin Moira Jones, M.D.
    • Nancy E. Paradies, Ph.D.
    • Pengchin Chen Ph.D.
    • Karen L. Fink, M.D., PH.D.
    • Oded Ben-Yoseph, Ph.D.
    • Mark A. Pershouse Ph.D.
    • John H. Sampson, M.D.
  • Basic Brain Tumor Research, PIs David James, Ph.D., Joe Petronio, M.D. Emory University,
  • Central Bain Tumor Registry of the United States, Founding and Sustaining Grant, Central Brain Tumor Registry

1993 Research Funded

Basic Research

  • New York University, PI Dr. Jeff Allen,
  • Los Angeles Children’s Hospital, PI, Corey Raffel, M.D.
  • University of Michigan, PI, Karin Murasko, M.D.
  • M.D. Anderson Cancer Center, PI, Victor Levin, M.D. Basic Laboratory Research
  • University of Washington Medical Center, PI, Mitchel Berger, M.D.
  • Children’s Hospital of Columbus, PI, Frederick B. Ruymann, M.D.
  • Johns Hopkins Oncology Center, PI Bert Vogelstein, M.D.
  • Mayo Clinic Research Hospital, PI Richard Jenkins
  • Research Fellowships American Brain Tumor Association
  • Research Support – Brain Tumor Foundation for Children for Dr. David James, Ph.D. Emory University
  • Central Brain Tumor Registry of the United States, Sustaining Grant

1992 Research Funding

Basic Research

  • Pilot Study to Determine the Feasibility of Establishing a Brain Tumor Registry in the United States, Central Brain Tumor Registry of the United States, Sustaining Grant
  • Research Fellowships – American Brain Tumor Association
  • M.D. Anderson Cancer, Basic Brain Tumor Research Support, PI Victor Levin, M.D.
  • Johns Hopkins Oncology Center, Basic Brain Tumor Research, PI Bert Vogelstein

1991 -1984 Research Funded

  • Emory University – David James, Ph.D.
  • Central Brain tumor Registry

     

     

     

     

     

     


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